Objective: Although microsurgical varicocelectomy improves semen parameters in many infertile men with varicocele, postoperative outcomes remain heterogeneous. Identifying reliable preoperative predictors of surgical success is therefore clinically important. The triglyceride–glucose (TyG) index has emerged as a simple and practical surrogate marker of insulin resistance (IR).
We aimed to evaluate the predictive value of the TyG index for varicocelectomy success.Methods: Patients who underwent microsurgical subinguinal varicocelectomy between 2019 and 2024 were retrospectively analyzed. The TyG index was calculated using fasting triglyceride and fasting blood glucose levels.
Semen analyses were performed preoperatively and six months postoperatively. Surgical success was defined as a >50% increase in postoperative total motile sperm count (TMSC), or >100% in patients with baseline TMSC
