Objectives: The aim of this study is to compare the cytotoxicity of teething gels with different contents and their effects on in vitro wound healing. Materials and Methods: The viability values of teething gels applied on human gingival fibroblast cells were evaluated and their cytotoxicity and effects on wound healing were investigated by scratch test.
Results: The cytotoxicity of 9 different teething gels on human gingival fibroblast cells and their effects on in-vitro wound healing at 24 and 48 hours were compared. The Lidocaine hydrochloride+cetylpridinium chloride based gel group had the most cytotoxic effect on human gingival fibroblast cells among teething gels.
Conclusion: Considering the results of our study, the necessity of using teething gels during the eruption period is controversial.