Aim: Distinguishing complicated from uncomplicated appendicitis is important for patient management. Readily available biomarkers such as serum lactate and C-reactive protein (CRP) may contribute to this process, although their diagnostic accuracy remains debated.Material and Methods: This retrospective study included 156 patients who underwent appendectomy between 2018 and 2024.
Patients were grouped as complicated or uncomplicated based on operative and histopathological findings. Preoperative serum lactate and CRP were analyzed using ROC curves, and multivariate logistic regression was performed to identify potential predictors.Results: Complicated appendicitis (n=60, 38.5%) was associated with higher lactate (median 2.5 vs 1.6 mmol/L, p