Objective: This study aimed to compare retrograde intramedullary nailing (RIMN) and femoral locked plating (FLP) in the management of periprosthetic supracondylar femur fractures (PSFF) following total knee arthroplasty (TKA), focusing on fracture healing, blood loss, functional outcomes, and complication rates.

Methods: Thirty-one patients surgically treated for PSFF between 2015 and 2021 were retrospectively analyzed. According to the fixation method, patients were divided into two groups: FLP (n=19) and RIMN (n=12). Group allocation was based on fracture pattern, distal fragment length, and prosthesis compatibility.

Fractures were classified according to the Su system. Operative parameters, intraoperative blood loss, transfusion requirement, union time, complications, and functional outcomes (Knee Society Score, KSS) were evaluated. Statistical analysis was performed using SPSS 23.0, with a significance level of p 0.05).

The RIMN group showed significantly lower intraoperative blood loss and transfusion requirements (p