More than 15 years ago, the original Sub-Saharan Africa Survey of Heart Failure (THESUS-HF) provided one of the first prospective, multinational descriptions of acute heart failure in sub-Saharan Africa.1 THESUS-HF found that patients with acute heart failure in sub-Saharan Africa were young, with near-equal incidence in men and women, that incidence was driven overwhelmingly by non-ischaemic disease, especially hypertensive and rheumatic heart diseases, and that short-term prognosis was poor.1 The study reframed heart failure in Africa as a distinct clinical entity rather than a footnote to high-income cohorts.
Kaynak: The Lancet
